The shape of the moral life is determined for Christians at least in part by beliefs peculiar to Christians, and a perennial problem for Christian ethics is relating that peculiar understanding to more general claims about moral knowledge. Since the problem is perennial, I propose not to solve it but to think about it. I do so by considering first the sense in which Christian ethics may be a kind of "insider's" ethic-the shared language of believers. Despite the (...) strengths of such a view, it may too greatly restrict both human and divine freedom. Having considered its difficulties from both those angles, I return to the sense of Christian life as a tradition of conduct in order to illustrate the importance of such a vision in our cultural setting. (shrink)

L'oeuvre du philosophe Paul Gilbert, jésuite belge professeur de métaphysique depuis vingt-cinq ans à l'Université Grégorienne, est considérable et mérite d'être mieux connue. Après avoir étudié les écrits de saint Anselme (Dire l'ineffable, 1984), Paul Gilbert a questionné la métaphysique classique, sous l'influence de la philosophie réflexive (La Simplicité du principe, 1994). Il a ensuite souligné les chances offertes à la réflexion fondamentale par l'analogie, thème classique mais oublié (La Patience d'être, 1996, et Sapere e sperare, 2003). Plus (...) récemment, il a abordé la question de la violence, ce mal- être si commun (Violence et compassion, 2009). En 1997 déjà, son travail a été récompensé du prix Cardinal Mercier de l'U.C.Louvain-la-Neuve. Durant de nombreuses années, Paul Gilbert a été professeur invité à l'Institut catholique de Paris. A l'occasion de son éméritat dans cette institution, un colloque y a été organisé. Dans leurs communications, S. Bonanni, Ph. Capelle-Dumont, S. D'Agostino, E. Gabellieri, J. de Gramont, 1. Malaguti, R. Repole et E. Tourpe reprennent et développent l'élaboration de la pensée de Paul Gilbert. Ce dernier fait écho à chacune d'elles et, dans un exposé final, retrace son propre itinéraire intellectuel. (shrink)

A definition of [George] Eliot as renunciatory culture-mother may seem an odd preface to a discussion of Silas Marner since, of all her novels, this richly constructed work is the one in which the empty pack of daughterhood appears fullest, the honey of femininity most unpunished. I want to argue, however, that this “legendary tale,” whose status as a schoolroom classic makes it almost as much a textbook as a novel, examines the relationship between woman’s fate and the structure of (...) society in order to explicate the meaning of the empty pack of daughterhood. More specifically, this story of an adoptive father, an orphan daughter, and a dead mother broods on events that are actually or symbolically situated on the margins or boundaries of society, where culture must enter into a dialectical struggle with nature, in order to show how the young female human animal is converted into the human daughter, wife, and mother. Finally, then, this fictionalized “daughteronomy” becomes a female myth of origin narrated by a severe literary mother uses the vehicle of a half-allegorical family romance to urge acquiescence in the law of the Father.If Silas Marner is not obviously a story about the empty pack of daughterhood, it is plainly, of course, a “legendary tale” about a wanderer with a heavy yet empty pack. In fact, it is through the image of the packman that the story, in Eliot’s own words, “came across my other plans by a sudden inspiration”—and, clearly, her vision of this burdened outsider is a re-vision of the Romantic wanderer who haunts the borders of society, seeking a local habitation and a name.11 I would argue further, though, that Eliot’s depiction of Silas Marner’s alienation begins to explain Ruby Redinger’s sense that the author of this “fluid and metaphoric” story “is” both Eppie, the redemptive daughter, and Silas, the redeemed father. For in examining the outcast weaver’s marginality, this novelist of the “hidden life” examines also her own female disinheritance and marginality.12 11. Eliot to Blackwood, 12 Jan. 1861, quoted in Ruby V. Redinger, George Eliot: The Emergent Self , p. 436. As Susan Garber has suggested to me, the resonant image of the “packman” may be associated with the figure of Bob Jakin in The Mill on the Floss , the itinerant pack-bearing peddler who brings Maggie Tulliver a number of books, the most crucial of which is Tomas à Kempis’ treatise on Christian renunciation .12. Rediner, George Eliot, p. 439; Eliot, “Finale,” Middlemarch, p. 896. Sandra M. Gilbert, now professor of English at the University of California, Davis, will join the Department of English at Princeton University in fall 1985. Her most recent works include a collection of poems, Emily’s Bread , and, coedited with Susan Gubar, The Norton Anthology of Literature by Women: The Tradition in English . In addition, she is at work on Mother Rites: Studies in Literature and Maternity, a project from which “Life’s Empty Pack” is drawn, and, with Susan Gubar, on No Man’s Land: The Place of the Woman Writer in the Twentieth Century, a sequel to their collaborative Madwoman in the Attic: The Woman Writer and the Nineteenth-Century Literary Imagination . “Costumes of the Mind: Transvestitism as Metaphor in Modern Literature” appeared in the Winter 1980 issue of Critical Inquiry. (shrink)

How should we live? What kind of people should we be? What meaning is there in our day-to-day existence? What are the truly important things? We live in turbulent times. Torrents of information, fractured families, and politically correct rhetoric color our understanding of ourselves, each other, and the world. We are sorely in need of moral compasses. In his timely and provocative work, Things That Count, ethicist and theologian Gilbert Meilaender provides us with just such a guide. Whether explicating (...) When Harry Met Sally or John Updike's fiction, meditating on the works of C. S. Lewis or St. Augustine, or presenting a different look at such controversial issues as cloning and homosexuality, Meilaender provides an ethic that ignores neither our humanity nor our thirst for rectitude. (shrink)

Constantine’s adherence to Christianity was a long process conditioned by personal motivations, as well as cultural and political factors. He observed the heathen cults and he did not recognize himself as a christian until the year 314, in his letter to the bishops met in Arelate. Since 324, after the defeat of Licinius, he declared his faith in the One and Only True God in different official texts. He resolved to receive the baptism a few days before his death, (...) in 337, perhaps in the hope of healing fromhis illness. His concept of Christianity was the one of an utilitarian religion, that offered him protection in war and guaranteed his authority in peace with the support of the Church. (shrink)

In a time of intensified interest in an "ethic of virtue," Josef Pieper stands out as one who has pondered and written about the virtues for many years. This paper explores some aspects of Pieper's thought about the virtues and focuses especially on four problems: (1) the question of the unity of the virtues; (2) the relation between natural and theological virtues; (3) the dangers for Christian ethics of picturing virtue as habitual; and (4) the question whether virtue needs (...) any reward beyond virtue itself. (shrink)

The author suggests that Christian participation in public policy deliberations about bioethical issues may be helped by structures which do not require the search for consensus (or, in particular, the kind of ‘overlapping consensus’ favoured by Rawlsians) on policy. This argument is made, first, by a general discussion of the place of religious visions within public discourse and, second, by an examination of the structure and some of the reports of the President’s Council on Bioethics (USA).

First published in 1964, this is a short collection of both literary and philosophical essays. Whilst two essays consider Greek literature written at the point at which the Athenian empire was breaking apart, another group explore the background from which Christianity arose, considering Paganism and the religious philosophy at the time of Christ. These, in particular, display Gilbert Murray’s ‘profound belief in ethics and disbelief in all revelational religions’ as well as his conviction that the roots of our society (...) lie within Greek civilization. Finally, there is an interesting discussion of Order and the motives of those who seek to overthrow it. (shrink)

This essay considers what it means to work within and attempt to retrieve aspects of a tradition of thought, in particular, the Christian tradition. Doing so places us in close proximity to certain conversation partners, but it does so without closing off possible enrichment from those who do not share our tradition. Perhaps the most critical issue involves freedom—that is, whether retrieving one's tradition undermines our own freedom or our recognition of God's. As an illustration of thinking within the (...) Christian tradition, the essay then considers the concept of a person, attempting to distinguish it from the more recent language of personhood. (shrink)

Offers a coherent, critical account of the theological visions that Lewis develops throughout his work, providing a unified introduction to his theology and an understanding of key social and ethical themes that have made him so influential. Works discussed include The Screwtape Letters, Surprised by Joy, and The Horse and His Boy. First published in 1978, this edition contains a new preface by the author, noting recent scholarship. Annotation copyrighted by Book News, Inc., Portland, OR.

The text in which the original JRE editors announced the mission of their newly launched scholarly journal is susceptible to different readings. While Ronald Green has interpreted it as an intention to "effect" a "movement from Christian ethics to religious ethics," the author expresses doubt that any such general framework of "religious ethics" can be discerned in or imposed on distinctive religious traditions. He suggests that the problem of "parochialism and Western bias" is best addressed not through the imperialism (...) of the generic but through sustained attention to the distinctive and particular in all its variations. (shrink)

This study deals with the transformations of a number of topics of Aristotelian political philosophy provoked by their crossing with the Augustinian interpretation of Christian doctrine, promoted by Thomas Aquinas in his Treatise on the Kingdom. The following is a review of the place of the universality of politics in Aquinas’s text, which in Aristotle’s philosophy was linked to political naturalism and that in Thomist reception seems to tend towards a supernatural and divine scenario. In order to evaluate this (...) conjecture we will refer to the causes and ends attributed by Thomas to the dominion of man over man, trying to recognize the place occupied by political virtue in this approach. The proposed hypothesis is that Thomas’s characterization of the political model of the kingdom implies a bifurcation in the end to which the political community aims, all of which would propitiate the de-universalization of politics itself. (shrink)

Être responsable de notre conduite passée, c’est, en un sens, devoir en répondre. Cela signifie d’accepter qu’on en est l’auteur, à titre d’individu ou de membre d’un groupe. Mais cela implique aussi de devoir la défendre, c’est-à-dire de la justifier si possible ou de l’excuser et parfois d’en accepter les conséquences négatives. Bref, si nous sommes responsables, c’est que nous sommes concernés et que nous devons réagir. À la difficulté psychologique de cette prise de responsabilité s’ajoutent des défis intellectuels majeurs. (...) Peut-on être responsables si notre conduite est due à des mouvements d’atomes déterminés ou soumis au hasard? Comment pourrait-il y avoir responsabilité à titre de membre d’un groupe qui échappe à notre contrôle? -/- Ce livre contient trois chapitres principaux (« le réseau de la responsabilité », « responsabilité et métaphysique », « responsabilité et société ») et deux analyses de textes importants (un extrait du livre III de l'Éthique à Nicomaque et « La responsabilité collective et ses implications » de Margaret Gilbert). -/- // -/- To be responsible for our past conduct is, in a sense, to have the duty to answer for it. This duty implies accepting that we are its author, either qua individual or qua member of a group. It may also imply defending our past conduct, by justifying or excusing it or, in the absence of a good defence, accepting adverse consequences. If we are responsible, we are concerned and must act. Clearly, taking our responsibilities is psychologically difficult; but it also poses tricky intellectual challenges. Can we be responsible for our conduct if it is due to the determined or random movements of atoms? Can we be responsible as a member of a group whose behaviour lies outside of our control? -/- This book contains three main chapters ("The network of responsibility", "responsibility and metaphysics", and "responsability and society"), as well as comments on two seminal texts (an extract of Aristotle's Nicomachean Ethics, Book III and Margaret Gilbert's "Collective Responsibility and its Implications"). (shrink)

The Oxford Handbooks series is a major new initiative in academic publishing. Each volume offers an authoritative and up-to-date survey of original research in a particular subject area. Specially commissioned essays from leading figures in the discipline give critical examinations of the progress and direction of debates. The Oxford Handbook of Theological Ethics offers the most authoritative and compelling guide to the discipline. Thirty of the world's most distinguished specialists provide new essays in order to offer a survey of and (...) analysis of the subject. Ethics is first placed firmly within the Christian theological tradition, from which thought and action can never be neatly separated. Four sections then explore the sources of Christian moral knowledge (scripture, divine commands, church tradition, reason and natural law, experience); the structure of the Christian life (vocation, virtue, rules, responsibility, death); the spirit of the Christian life (faith, hope, love); and the spheres of the Christian life (government, family, economy, culture, church). The final section of the Handbook contains essays discussing and evaluating certain scholarly works that have in the past influentially offered (different) visions of how best to structure the field of theological ethics. Unlike any other book now available, the Handbook's unrivalled breadth and depth make it the definitive reference work for all students and academics who want to explore more fully essential topics in Christian ethics. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:"Spirituality":"Weasel-Word" or Gateway to New Understanding?Peter Gilbert (bio)Keywordsspirituality, faith communities, NIMHEVisiting the Samuel Palmer Exhibition at the British Museum, I was struck, not only by the spiritual power of the paintings, especially in the late Shoreham period such as, my favorite: The Magic Apple Tree (circa 1830)—but how Palmer appeared to bring both Christian and Pantheistic themes into his work. The museum's exhibition collator remarks that Palmer (...) saw the fruitfulness of the earth as an intimation of Divine creativity. The artist sought to capture "The essential vivifying spirit, vital spark" (Palmer's words) of the physical world in which we live.I was reminded as I moved from The Magic Apple Tree, to In a Shoreham Garden, and The Golden Valley, how these paintings had been used by a record company when they had issued all of Ralph Vaughan Williams' orchestral and choral works in the 1970s, to mark his anniversary. Vaughan Williams was not a signed up Christian, but many of his choral works express a strong yearning for the transcendent using Christian imagery. The day before I visited the Palmer exhibition, I listened to Professor Robert Winston on Start the Week (28th November, 2005), in which he spoke of his BBC series The Story of God (Winston, 2005). As a scientist, Winston is intrigued as to why humans seek the transcendent. He continually refers to this desired other as "God," although I think it would be more accurate to call it a search for the transcendent. Winston puzzles over why there appears to be "a God-shaped hole" within humanity (Start the Week, November, 28, 2005), and again, as a scientist, postulates that: "the more we understand about science, the less we understand about the Universe."In the light of the most popular films and books at present, the search for something beyond ourselves appears to be very much at the center, rather than at the periphery of humanity's consciousness at the present time. Reading Philip Pullman's His Dark Materials trilogy, and reading his various essays, we are struck by his articulation of the human search:We need a story, a myth that does what the traditional religious stories did. It must explain. It must satisfy our hunger for a Why... There are two kinds of Why, and our story must deal with both. There's the one that asks What brought us here? and the other that asks What are we here for?(Pullman, 2001)The author's article is very helpful in its practical approach to psychotherapy and spirituality. I particularly liked her reference to the work of Charles Corr (1991) and his work with people [End Page 197] who are dying and considering the physical, psychological, social, and spiritual aspects of the last days. The spiritual aspects being around identifying, developing, or reaffirming spiritual sources of energy and hope. This is the kind of approach that the National Institute for Mental Health in England (NIMHE) national Project on Spirituality and Mental Health has been engaged in since 2001, the approach being to stress the spiritual dimension as an integral part of a whole person and whole systems approach to mental health; work with mental health services and their partners to engage with this agenda; and work toward a better understanding between faith communities and mental health services (see Gilbert and Nicholls, 2003). Service users and their carers are increasingly stating strongly to services that they wish to have their spiritual dimension and spiritual needs addressed properly—and certainly not in a "tick-box" method! The author quotes Samson and Zerter (2003) as saying that the person's spiritual dimension "draws a thread of identity, relationship, meaning and purpose, which weave through each of these aspects" (i.e. the life events and other aspects of their being).I welcome the author's stress on a "relational approach," and her breadth of reference, for example, the diary of Marcus Aurelius, the Roman emperor and philosopher, but I had some concerns about her use of the term personal theology, and talk of the personal aspect of religion and "the Divine," in that I think that this could... (shrink)

At its founding and during its first three decades, the Carthusian order developed a distinctive and forceful concept of communication among the members and between the members and the extramural world.2 Saint Bruno’s life, contemporary twelfth-century exegesis, and the physical situation of La Grande Chartreuse established the necessary context in which this concept evolved. A review of historical background, the relevant documentary texts, and early development demonstrate the shaping of two steps in this concept. Close reading of the principal testimonies (...) of Carthusians Bruno, Guigo I, Guigo II, and some other witnesses, as well as of some passages in Saint Augustine, argues that Carthusian scribal work was more preliminary practice for spiritual development than it was the sacralization of codices and texts. The two-step structure, composed of contrary movements of presentation and effacement, guarded what the Carthusians regarded as spiritual activity within a changing historical environment and became a fundamental part of Latin Christian mysticism in the fourteenth and fifteenth centuries. (shrink)

The papal encyclical "Veritatis Splendor", issued in 1993, treats in detail important questions of moral theory and is clearly an important moment in the history of Christian ethics. Supporters and critics of the encyclical have tended to focus attention upon its defense of an objectively true morality and its contention that some acts are intrinsically evil. This discussion overlooks questions that one might address to the encyclical from the perspective of the Reformation. The most fundamental of these is the (...) encyclical's understanding of the place of faith in the Christian life. I will explore this chiefly by contrasting the ways in which John Paul II and Karl Barth understand the story of the rich young ruler and by exploring the possibility that one might cling to God while deliberately choosing evil. (shrink)

This article intends to show the topicality of the dragon theme among children in Quebec, first of all from a study of cultural productions (books and films) intended for them, but also from an analysis of anthropological tests (AT.9s) completed by 194 children aged 6 to 12 years between 2009 and 2019. This analysis of the AT.9s, contextualized by that of the children’s surrounding culture, allows us to conclude that the theme of the dragon persists, that there is a plurality (...) of interpretations of this figure, and that the theory of anthropological structures of the imaginary (G. Durand) is relevant to our time, including with children. From all of this emerges an observation: from the age of 6, children already possess the anthropological structures but also certain cultural figures that are found in adults and the great cultures of humanity. (shrink)

El artículo estudia cómo la fenomenología puede contribuir al quehacer teológico. A tal fin, el prof. Gilbert comienza por identificar los inicios de la fenomenología. Seguidamente, presenta lo que él denomina fenomenología “descriptiva”, marcada por las ciencias humanas, que sirvió para reconocer las características esenciales de la religión. Pero la fenomenología puede dar un paso más, ya estrictamente filosófico, para elaborar un modo de fenomenología “especulativa”. Finalmente, el artículo indica las aportaciones de esta esta fenomenológica al desarrollo de la (...) teología, estudiando las propuestas de Michel Henry, Jean-Luc Marion y Emmanuel Falque. (shrink)

Gilbert Meilaender has been an important contributor to the field of bioethics for decades. His insistence that there is a natural teleology of the body that should constrain ambitions of the will in bioethics deserves careful attention. This article examines the idea of a natural teleology of the body as it applies to human oocytes. It argues that approaching human eggs in terms of their telos rather than their moral status is useful. The article examines how Meilaender deploys the (...) idea of a natural teleology to reject John Robertson’s work on assisted reproduction, particularly his preoccupation with procreative liberty. Finally, the article raises questions about the sharp contrast Meilaender draws between teleology and intentionality. (shrink)

A fundamental theme in Gilbert Meilaender’s work on bioethical issues is the relationship between the ethical claims of finitude and of freedom. This article identifies two ways in which Meilaender articulates this relationship and proposes a third way which avoids the limitations of the first two ways while serving Meilaender’s purpose, which is to redress what he sees as an imbalance in favor of the claims of freedom over those of finitude in contemporary biomedicine and bioethics. The article ends (...) by suggesting that Meilaender’s purpose would be best served by avoiding tensions between finitude and freedom as the third way does. (shrink)

This article provides a friendly criticism of Meilaender’s positions on the beginning of life and decision making at the end of life. It is argued that his version of the self is narrowly physicalist and individualist with no room for the essentially social and psychological parts of identity or selfhood. That in turn leads to his rigoristic or tutioristic judgments on end of life care.

Name der Zeitschrift: Kierkegaard Studies Yearbook Jahrgang: 2013 Heft: 1 Seiten: 451-472.

This paper explores the political thought of Michel Foucault, which is anchored on his philosophy of subjectivation or the transformation of individuals into subjects. It presents his ideas of the State from the point of view of specific strategies and practices of power used in the transformation of individuals into subjects. It also presents his analysis of government as an organization that looks after the achievement of individual's goals and interests. The goal of government is not to achieve the common (...) good but to realize the suitable end of each individual. (shrink)

How do Christian beliefs about human nature and destiny set possibilities for and limits to our political aspirations and goals? Specifically, what is the proper relation between a theology of creation and soteriology in Christian political ethics? This article considers these questions through an interpretation of the development of Gilbert Meilaender’s political thought. It concludes with some questions about that development as it stands, as well as from the standpoint of salient themes in Roman Catholic social teaching.

In this paper I will introduce a practical explication for the notion of expertise. At first, I motivate this attempt by taking a look on recent debates which display great disagreement about whether and how to define expertise in the first place. After that I will introduce the methodology of practical explications in the spirit of Edward Craig’s Knowledge and the state of nature along with some conditions of adequacy taken from ordinary and scientific language. This eventually culminates in the (...) respective explication of expertise according to which this term essentially refers to a certain kind of service-relation. This is why expertise should be considered as a predominantly social kind. This article will end up with a discussion of advantages and prima facie plausible objections against my account of expertise. (shrink)

In a recent paper, Gilbert Meilaender argues that Christian ethics must not be consequentialist. Though Meilaender does indicate some problems which may exist with certain consequentialist theories, those problems do not exclude all types of consequentialist theories from consideration as Christian ethical theories. A consequentialism like R. M. Hare’s offers virtually all the advantages Meilaender claims for his Christian deontological view. Moreover. Meilaender has overlooked certain advantages of consequentialism and certain disadvantages of the sort of deontological (...) theory he espouses. (shrink)

The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

Ontologies, as the term is used in informatics, are structured vocabularies comprised of human- and computer-interpretable terms and relations that represent entities and relationships. Within informatics fields, ontologies play an important role in knowledge and data standardization, representation, integra- tion, sharing and analysis. They have also become a foundation of artificial intelligence (AI) research. In what follows, we outline the Coronavirus Infectious Disease Ontology (CIDO), which covers multiple areas in the domain of coronavirus diseases, including etiology, transmission, epidemiology, pathogenesis, diagnosis, (...) prevention, and treatment. We emphasize CIDO development relevant to COVID-19. (shrink)

Although an invasive medical intervention, Deep Brain Stimulation (DBS) has been regarded as an efficient and safe treatment of Parkinson’s disease for the last 20 years. In terms of clinical ethics, it is worth asking whether the use of DBS may have unanticipated negative effects similar to those associated with other types of psychosurgery. Clinical studies of epileptic patients who have undergone an anterior temporal lobectomy have identified a range of side effects and complications in a number of domains: psychological, (...) behavioural, affective and social. In many cases, patients express difficulty adjusting from being chronically ill to their new status as ‘treated’ or ‘seizure free’. This postoperative response adjustment has been described in the literature on epilepsy as the ‘Burden of Normality’ (BoN) syndrome. Most of the discussion about DBS postoperative changes to self is focused on abnormal side effects caused by the intervention (ie, hypersexuality, hypomania, etc). By contrast, relatively little attention is paid to the idea that successfully ‘treated’ individuals might experience difficulties in adjusting to becoming ‘normal’. The purpose of this paper is (1) to articulate the postoperative DBS psychosocial adjustment process in terms of the BoN syndrome, (2) to address whether the BoN syndrome illustrates that DBS treatment poses a threat to the patient’s identity, and (3) to examine whether the current framework for rehabilitation after DBS procedures should be updated and take into account the BoN syndrome as a postoperative self-change response. (shrink)

Over a period of 19 months in 2006 and 2007, Mattel recalled approximately 14 million toys. The company was subjected to numerous lawsuits and regulatory actions and suffered severe damage to its reputation. Two issues were involved: excessive levels of lead in numerous toy surface paints and small detachable magnets in some toys, which could be swallowed. An examination of the facts shows that two different ethical situations were involved—one concerning product design and the other concerning manufacturing practices of Mattel's (...) Chinese contractors and subcontractors. The ethical obligations of the company and individuals within the company in the two situations were quite different, and illustrate problems faced by companies in managing their global supply chains. (shrink)

Current COVID-19 pandemic and previous SARS/MERS outbreaks have caused a series of major crises to global public health. We must integrate the large and exponentially growing amount of heterogeneous coronavirus data to better understand coronaviruses and associated disease mechanisms, in the interest of developing effective and safe vaccines and drugs. Ontologies have emerged to play an important role in standard knowledge and data representation, integration, sharing, and analysis. We have initiated the development of the community-based Coronavirus Infectious Disease Ontology (CIDO). (...) As an Open Biomedical Ontology (OBO) library ontology, CIDO is an open source and interoperable with other existing OBO ontologies. In this article, the general architecture and the design patterns of the CIDO are introduced, CIDO representation of coronaviruses, phenotypes, anti-coronavirus drugs and medical devices (e.g. ventilators) are illustrated, and an application of CIDO implemented to identify repurposable drug candidates for effective and safe COVID-19 treatment is presented. (shrink)

Pour Aristote, la Cité commence lorsque les hommes qui la composent passent de la multiplicité quantitative à la diversité qualitative, c'est-à-dire qu'elle naît avec la différence. Cette différenciation est analysée principalement au niveau des formes de commandement et de la justice. Dès lors, on comprend qu'Aristote soit conduit à une critique radicale de la conception platonicienne de la Cité, laquelle doit manifester le plus haut degré possible d'unification. Cette critique se résume dans le rejet très argumenté de la mise en (...) commun des biens, des femmes et des enfants. Elle ne témoigne pas de la part d'Aristote, comme on l'a dit, d'une évocation approximative des thèses platoniciennes, mais d'une référence précise au texte de Platon. According to Aristote, the City begins when those who belong to it change from quantitative multiplicity to qualitative multifariousness, i.e. it is given birth through différence. Such a differenciation is mainly analyzed on the level of forms of command and justice. Hence one understands Aristotle to have been driven to a radical criticism of the conception Plato had of the City, the latter liable to manifest the highest degree of unification. Such a criticism can be summed up in the very argumented rejection of the sharing in common of goods, women and children. It does not evidence, on the part of Aristotle, as was said previously, an approximative evocation of Plato's theses, but rather a precise reference to Plato's text. (shrink)

English summary: This volume looks at the so far little studied connections between the philosophy of Schelling and the historiographic waves in theological, philosophical and historical discourse during the first half of the 19th century. The reception of Schelling in theology, philosophy and history relates primarily to his writings around 1800. The essays in this volume firstly analyze the considerable impact that these texts had on the structure of contemporary debate. Secondly, they analyze the interdependence of the historical theology that (...) was beginning to take root and Schelling's emerging later philosophy. Thirdly, they examine the reception of Schelling's philosophy of history from the perspective of Friedrich Schleiermacher and historical academic discourse, as well as David Friedrich Strauss, Ferdinand Christian Baur and the Landhut Romantics. German description: Der vorliegende Band thematisiert die bislang nur wenig erforschten Zusammenhange zwischen der Philosophie Schellings und den Historisierungsschuben in den theologischen, philosophischen und geschichtswissenschaftlichen Diskursen der ersten Halfte des 19. Jahrhunderts. Die Rezeption Schellings in Theologie, Philosophie und Geschichtswissenschaft bezieht sich vor allem auf dessen Schriften um 1800. Die Beitrage des Bandes untersuchen sowohl die breite Wirkung dieser Texte in den zeitgenossischen Debattenkonstellationen sowie die Wechselwirkungen zwischen der sich etablierenden historischen Theologie und der Herausbildung von Schellings Spatphilosophie als auch die Rezeption der Geschichtsphilosophie Schellings bei Friedrich Schleiermacher sowie in den geschichtswissenschaftlichen Diskursen, bei David Friedrich Strauss, Ferdinand Christian Baur sowie in der Landshuter Romantik. Mit Beitragen von: Christopher Arnold, Ulrich Barth, Christian Danz, Georg Essen, Malte Dominik Kruger, Christof Landmesser, Michael Murrmann-Kahl, Georg Neugebauer, Jan Rohls, Oliver Wintzek, Johannes Zachhuber. (shrink)

A fresh interpretation of Jeremy Bentham, finding that his “radical foolery” embodied a social ethics that was revolutionary for its time. Jeremy Bentham (1748–1832) is best remembered today as the founder of utilitarianism (a philosophy infamously abused by the Victorians) and the conceiver of the Panopticon, the circular prison house in which all prisoners could be seen by an unseen observer—later seized upon by Michel Foucault as the apotheosis of the neoliberal control society. In this volume in the Untimely Meditation (...) series, Christian Welzbacher offers a new interpretation of Bentham, arguing that his “radical foolery” (paraphrasing Goethe's characterization of Bentham) actually embodied a social ethics that was new for its time and demands proper historical contextualization rather than retroactive analysis from the vantage point of late capitalism. Welzbacher provides just such an analysis, offering an account of the two great utilitarian projects that occupied Bentham all his life: the Panopticon and the Auto-Icon. Welzbacher rescues the Panopticon from the misapprehensions of Foucault, Orwell, and Lacan, arguing that Bentham saw the Panopticon as a pedagogical instrument incorporating the tenets of reason; construction and function, plan and influence, architecture and politics are brought into alignment. Bentham extolled the discovery in words that could easily be ascribed to Le Corbusier, Bruno Taut, or any other modernist architect. The Auto-Icon expressed Bentham's theories that the dead should benefit later generations; these theories were effectively sealed when Bentham decided to have his body preserved and put on display. (It can be seen today in a cabinet at University College London.) He also donated his inner organs to science—a practice outlawed at the time—and posthumously stage-managed his own ceremonial autopsy. Welzbacher reveals a Bentham who raised questions that feel familiar and current, invoking topoi that would come to define the modern era and that reverberate to this day. (shrink)

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

Can it ever be appropriate to feel guilt just because one's group has acted badly? Some say no, citing supposed features of guilt feelings as such. If one understands group action according to my plural subject account of groups, however, one can argue for the appropriateness of feeling guilt just because one's group has acted badly - a feeling that often occurs. In so arguing I sketch a plural subject account of groups, group intentions and group actions: for a group (...) to intend (in the relevant sense) is for its members to be jointly committed to intend that such-and-such as a body. Individual group members need not be directly involved in the formation of the intention in order to participate in such a joint commitment. The core concept of joint commitment is in an important way holistic, not being reducible to a set of personal commitments over which each party holds sway. (shrink)

El liberalismo de Carlos S. Nino evolucionó desde sus primeros trabajos vinculados al derecho penal, hacia la construcción de una teoría de la democracia deliberativa. Desde sus comienzos, siguiendo a los autores liberales clásicos como John Stuart Mill, hasta el final en donde adhirió a un liberalismo igualitario, hubo construcciones que acompañaron este proceso, como el concepto de autonomía personal, y también ciertos ideales morales, como un oposición concreta al perfeccionismo. El texto presenta al liberalismo de Nino al comienzo y (...) al final de su obra para mostrar que el antiperfeccionismo originado en el liberalismo clásico que servía de base para construir su concepción de la autonomía, se mantuvo inalterado durante todo este proceso de evolución dificultando la compatibilización de su teoría de la responsabilidad penal con su teoría de la democracia deliberativa, orientada hacia el liberalismo igualitario. (shrink)

Adorno's moral philosophy has often been accused of making aporetic prescriptions that are too taxing for moral agents. In this article, I defend his approach in terms of a theory of moral dilemmas. My guideline is Adorno's famous sentence that wrong life cannot be lived rightly. I argue that this claim is not distinctly prescriptive, as most of Adorno's critics believe, but is a claim about moral reality. Emphasizing realist aspects of his moral theory, I suggest that wrong life is (...) neither inconceivable nor an amoral or skeptical trope. Instead, Adorno's sentence about wrong life can be interpreted as a claim about the salience of particular moral facts. This, I conclude, allows Adorno to envisage moral reasons that motivate moral conduct case by case, although they are blocked overall. (shrink)

Des Herrn Doct. und Prof. Joachim Langens, oder, Der Theologischen Facultaet zu Halle Anmerckungen über des Herrn Hoff-Raths und Professor Christian Wolffens Metaphysicam ... nebst beygefügter Hr. Hoff-R. und Prof. Christian Wolffens gründlicher Antwort -- Herrn D. Joh. Francisci Buddei S.S. Theol. P.P.O. zu Jena Bedencken über die Wolffianische Philosophie, mit Anmerckungen erläutert von Christian Wolffen.